Pre-implantation Genetic testing for Aneuploidies (PGT-A)

Pre-implantation Genetic testing for Aneuploidies (PGT-A)

What is PGT-A testing?

Pre-implantation Genetic Testing for Aneuploidies (PGT-A), is a genetic test performed on embryos produced through IVF to screen for chromosomal abnormalities. PGT-A gives information about embryos’ genetic health to help select the best embryo for transfer and improve your chance of achieving a successful pregnancy. PGT-A was previously known as Pre-implantation Genetic Screening(PGS).

How it works?

PGT-A looks at the amount of genetic material within IVF embryos. This genetic material is contained inside structures called chromosomes. Chromosomes are important for healthy development and growth.

Embryos with the incorrect number of chromosomes (aneuploid embryos) mostly do not result in a successful pregnancy or if they do may lead to the birth of a child with a genetic condition. Embryos with the correct number of chromosomes (euploid embryos) have more chance of leading to a successful pregnancy. PGT-A identifies embryos with the correct number of chromosomes which when selected has best chances of leading to IVF success.

Who is PGT-A for?

PGT-A is appropriate for the vast majority of people undergoing IVF especially if you are 35 years old and above as aneuploidy risk increases with age, or if you have had previous pregnancy losses. As a woman ages, the potential for chromosomally abnormal embryos increases, despite the number of embryos produced.

Every woman is at risk of producing embryos with chromosomally abnormalities. PGT-A can help women of all ages increase their chances of a successful pregnancy.

Why use PGT-A?

Higher chance of pregnancy

Reduced risk of miscarriage

More confidence in transferring a single embryo, avoiding health risks associated with twin or triplet pregnancies

Reduced number of IVF cycles needed to achieve pregnancy, potentially reducing the time to pregnancy and the costs of extra cycles

 

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